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Can PBC lead to liver cancer? For example, in primary biliary cirrhosis (PBC) the bile ducts in the liver are damaged and even destroyed which can lead to cirrhosis. People with advanced PBC have a high risk of liver cancer.
How do they test for PBC? Typically, screening level blood tests show a higher than normal alkaline phosphatase (AP) level with a normal bilirubin. Anti-mitochondrial antibody (AMA) blood test - Up to 95% of patients with PBC will have a positive AMA test. This test is used to help confirm a diagnosis of PBC. mowydncphg